There are some things to point out about the 45 Super as I've played with it somewhat extensively. First is that using Starline 45 Super brass it can be loaded to duplicate 460 Rowland, the one drawback to that, if you want to call it that, is that the gun will require using a compensated barrel.
But also what I did was to lengthen the throat in the barrel in order to allow heavier (and sturdier) .452" revolver profile bullets in the .45 Super. Might not seem like much but it opens up the operating range of bullets which can exceed 300grs. There is truth that just running .45 ACP bullets fast doesn't really prove much as most of those aren't capable of handling the velocity real well, a 230gr might be okay at 1000 fps but act differently at 1350 fps, or a 185gr @ 1600 fps, which is doable from a 5" .45 Super with a comp. But run say a 250gr XTP, a revolver style bullet, to over 1300 fps and you've got a pretty big hammer. Similar things though could be said of 10mm, not all .400" JHP's fair well at higher speeds, many in fact do not.
But also what I did was to lengthen the throat in the barrel in order to allow heavier (and sturdier) .452" revolver profile bullets in the .45 Super. Might not seem like much but it opens up the operating range of bullets which can exceed 300grs. There is truth that just running .45 ACP bullets fast doesn't really prove much as most of those aren't capable of handling the velocity real well, a 230gr might be okay at 1000 fps but act differently at 1350 fps, or a 185gr @ 1600 fps, which is doable from a 5" .45 Super with a comp. But run say a 250gr XTP, a revolver style bullet, to over 1300 fps and you've got a pretty big hammer. Similar things though could be said of 10mm, not all .400" JHP's fair well at higher speeds, many in fact do not.