For me I like the S&W .44 Magnum and the .357 SIG.    The only issue I have with the 357 SIG is reloading the 357 SIG case is very hard to do without crushing the case neck.    The 40S&W is fun to shoot to .  I have a SIG P226 and can change out barrels to fire either .40S&W or 357 SIG.

I am Dr. David S DeMasi    I work as a college educator teaching Astrophysics for the last 12 years.    I love to develop rounds and have been employed to develop some rifle loads for the .223 WSSM and the 7MM BR.    I have been shooting the 10mm since its introduction by Colt on the BrenTen. My guns I own now are a Glock 20 with a Pyramid trigger assembly and steel guide rod which really makes this gun very nice to shoot.  I also have a Kimber Stainless Target II  10MM which is very enjoyable to shoot.   I have handguns in all different calibers and styles such as 44 magnum, 357 magnum, .50 S&W, 9mm, 40S&W, 45 acp, 32 acp, .380, 357 sig,  7mmBR, 7MM IHMSA, .223 all of them in handguns (the last three are in Remington XP-100.) and numerous .22 Long rifle pistols.    I use to shoot Silhouette Metallics up in Montana using the Smith and Wesson Model 29 Silhouette  w/ 10 inch barrel free standing and used my Wichita Arms 7mm IHMSA and the XP 100 7MM BR for creedmore .    I use to shoot long range target with my Steyr Mannlicher tactical rifle .300 Win Mag and also my Savage Longranger  22-250.    I am in California now and shooting is limited to what range will provide as I am not in Montana anymore.   The 10mm I find gives me a challenge to control a high caliber handgun without being as brutal as the Smith and Wesson Model 500 in 50 S&W 10" barrel.  I find the 10mm also is pretty good to use on hogs in Northern California.   I really enjoy working up loads that provide accuracy as well as enough power to do the job.  I find that Accurate Arms powder such as AA #7 , VV 3N37, and HS-6 can work out some very accurate rounds using 180 grain bullets and hunting loads as well.   None of the loads are anywhere near maximum pressures as more pressures cause extreme wear on the gun and do nto make for the most accurate loads.   Well take care and hope you enjoy your 10mm as it is a very nice gun to shoot.    DrDave